Product Name :
POLR3C Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
DNA directed III 62 kDa polypeptide antibody DNA-directed RNA polymerase III subunit C antibody DNA-directed RNA polymerase III subunit rpc3 antibody POLR3C antibody Polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody RNA polymerase C subunit 3 antibody RNA polymerase III 62 kDa subunit antibody RNA polymerase III C62 subunit antibody RNA polymerase III subunit C3 antibody RPC3 antibody 展开
Function :
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation.Formula of 1-Bromo-3-methylnaphthalene Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.Price of Monomethyl auristatin E Acts as nuclear and cytosolic DNA sensor involved in innate immune response.PMID:33636739 Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human POLR3C 21-120/534
Species reactivity:
Human
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
61 KDa
Positive control :