Product Name :
TNFAIP3 interacting protein 3 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
A20 binding inhibitor of NF kappa B activation 3 antibody ABIN 3 antibody ABIN 3 beta antibody FLJ21162 antibody LIND antibody Listeria induced antibody Listeria induced gene protein antibody TNFAIP3 interacting protein 3 antibody TNFAIP3 interacting protein 3 beta antibody TNIP3 antibody 展开
Function :
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate.3-Chloro-1H-pyrazole manufacturer Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3 51-150/325
Species reactivity:
Human, Mouse, Rat, Cow, Sheep
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.4-Hydroxybenzenesulfonyl chloride structure
ELTSA :
Molecular weight :
39 KDa
Positive control :
Highly expressed in lung, lymph node, thymus and fetal liver.PMID:33438379 Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL.