Product Name :
PTBP1 Recombinant Rabbit Monoclonal Antibody [JU41-20]
Predicted band size :
57 kDa
Observed band size :
57 kDa
Synonyms:
57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antibody HNRNPI antibody HNRPI antibody MGC10830 antibody MGC8461 antibody 展开
Function :
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PTBP1 aa 20-69 / 531.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JU41-20
RRID:
AB_3070678
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1-Methylcyclobutanecarboxylic acid site Aliquot store at -20℃ or -80℃.Phenylboronic acid site Avoid repeated freeze / thaw cycles.PMID:33557991
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
57 kDa
Positive control :
K562 cell lysate, Jurkat cell lysate, human tonsil tissue, human skin tissue, human kidney tissue, mouse colon tissue, human lymph nodes tissue,mouse large intestine tissue.