Product Name :
STIM2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
FLJ39527 antibody KIAA1482 antibody STIM 2 antibody STIM2 antibody STIM2_HUMAN antibody Stromal interaction molecule 2 antibody
Function :
Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Functions as a highly sensitive Ca2+ sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca2+-influx. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. Upon mild variations of the endoplasmic reticulum Ca2+ concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca2+ release-activated Ca2+ (CRAC) channels ORAI1, ORAI2 and ORAI3.1234616-13-7 uses May inhibit STIM1-mediated Ca2+ influx.136092-76-7 custom synthesis
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human STIM2 aa 1-140 / 746.PMID:33417324
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF-Cell
Coupling :
unconjugated
Clone number:
RRID:
AB_3069299
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 84 kDa
Positive control :
293T, AGS, Hela, human kidney tissue, human placenta tissue, mouse testis tissue.